Pentose phosphate printable worksheet purposegames. A redox independent role of the pentose phosphate pathway ppp during the oxidative stress response. The separation of ribulose phosphate from ribose phosphate and the demonstration that. Pentose phosphate pathway hexose monophosphate shunt. Pdf the pentose phosphate pathway is a metabolic redox. He describes in detail the two distinct modes in the pathway. Nadph which is generated in the oxidative branch of the pathway can feed back and inhibit the pathway. The biochemistry, metabolism and inherited defects of the pentose phosphate pathway. This second process is a complex sequence of reactions that let you change the c3, c4, c5, c6, and c7 pentose sugars to form finally glyceraldehyde3 phosphate and fructose 6 phosphate, which can go directly to glycolysis. The breakdown of the simple sugar, glucose, in glycolysis provides the first 6carbon molecule required for the pentose phosphate pathway. Pentose phosphate pathway uc berkeley mcb university of. A free powerpoint ppt presentation displayed as a flash slide show on id.
Regulation of the pentose phosphate pathway in cancer. Pentose phosphate pathway an overview sciencedirect topics. To relate defects in the pentose phosphate pathway to disease conditions. The pentose phosphate pathway aims to explore the pentose phosphate cycle and the practical techniques applied in its investigation. Pentose phosphate pathway free download as powerpoint presentation.
Pentose phosphate pathway khan academy free online. So, the pentose phosphate pathway is mainly focused on the creation of nadph, but our cells dont like to waste much of anything so there are other things this pathway can. The main focus of the book is the pentose phosphate cycle in animals as well as microorganisms, and does not discuss the one related to photosynthesis. The regulation of the oxidative phase of the pentose phosphate. Pentose phosphate pathway generation of nadph and pentoses overview function nadph production reducing power carrier synthetic pathways role as cellular antioxidants. Glucose 6p dehydrogenase deficency sexlinked trait cause oxidative stress under certain environmental conditions low levels of glutathione another genetic trait favored in malarial regions distorts surface of red blood cells targets them for destruction anitmalarial drugs cause hemolytic crisis by oxdiative. Ppt pentose phosphate pathway powerpoint presentation. The pentose phosphate pathway journal of biological chemistry.
Pentose phosphate pathway hexose monophosphate shunt gmch. Metabolism lecture 5 pentose phosphate pathway restricted for students enrolled in mcb102, uc berkeley, spring 2008 only. Pdf the biochemistry, metabolism and inherited defects. Pdf there is a paradox in the oxidizing phase of the phosphate pentose pathway that has not yet been solved. Group 2biochemistry pentose pathway in a relation to diabetes free download as powerpoint presentation. By printig out this quiz and taking it with pen and paper creates for a. Learn pentose phosphate pathway biochem biochemistry with free interactive flashcards. A redoxindependent role of the pentose phosphate pathway ppp during the oxidative stress response. Pentose phosphate pathway biomolecules medical specialties. If absent, the h2o2 would be converted to hydroxyl free radicals by fenton chemistry, which. Thus the unknown 2carbon fragment never occurred as a free entity.
Reactions of the pentose phosphate pathway occur in the cytosol in two phases oxidative non. Read and learn for free about the following article. The nonoxidative phase of the pentose phosphate pathway is initiated when the cell needs more nadph than ribose5 phosphate. The respiroscope is a glass apparatus consisting of a bulb like part with a bent neck and vertical tube. The city of pentos is one of the nine free cities across the narrow sea. Ganongs respiroscope, pentose phosphate pathway notes. Glycolysis, gluconeogenesis, and the pentose phosphate pathway. During the first step of glycolysis, glucose is transformed by the addition of a phosphate group, generating glucose6 phosphate, another 6carbon molecule.
The pentose phosphate pathway is a metabolic pathway parallel to glycolysis. Choose from 500 different sets of pentose phosphate pathway flashcards on quizlet. This worksheet is in pdf format and holds a printable version of the quiz pentose phosphate. Choose from 500 different sets of pentose phosphate pathway biochem biochemistry flashcards on quizlet. Pentose phosphate cycle an overview sciencedirect topics. Group 2biochemistrypentose pathway in a relation to. Transketolase genes are key ratelimiting enzymes in the nonoxidative part of the pentose phosphate pathway, which is an important metabolic pathway in ribose5 phosphate production. Learn pentose phosphate pathway with free interactive flashcards. Metabolism lecture 5 pentose phosphate pathway restricted for students enrolled in mcb102, uc berkeley, spring 2008 only regulation of the pentose phosphate pathway. The pentose phosphate shunt is a semiindependent alternative pathway that parallels glycolysis figure 1. What is the pentose phosphate pathway and its significance.
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